Vitamin D protects some against colorectal cancer

first_imgA new study by investigators at Dana-Farber Cancer Institute, a Harvard affiliate, demonstrates that vitamin D can protect some people with colorectal cancer by perking up the immune system’s vigilance against tumor cells.The research, published today by the journal Gut, represents the first time that a link between vitamin D and the immune response to cancer has been shown in a large human population. The finding adds to a growing body of research showing that vitamin D — known as the “sunshine vitamin” because it is produced by the body in response to sunlight exposure — plays a key role in cancer prevention.“People with high levels of vitamin D in their bloodstream have a lower overall risk of developing colorectal cancer,” said the study’s senior author, Shuji Ogino of Dana-Farber, the Harvard T.H. Chan School of Public Health, and Brigham and Women’s Hospital. “Laboratory research suggests that vitamin D boosts immune system function by activating T cells that recognize and attack cancer cells. In this study, we wanted to determine if these two phenomena are related: Does vitamin D’s role in the immune system account for the lower rates of colorectal cancer in people with high circulating levels of the vitamin?”Ogino and his colleagues theorized that if the two phenomena were connected, then people with high levels of vitamin D would be less likely to develop colorectal tumors permeated with large numbers of immune-system cells. Colorectal tumors that do develop in these individuals would, by the same logic, be more resistant to the immune response.To determine if this was in fact the case, the research team drew on data from 170,000 participants in the Nurses’ Health Study and Health Professionals Follow-Up Study, two long-term health-tracking research projects. Within this population, the scientists compared carefully selected groups of 318 colorectal cancer patients and 624 cancer-free individuals. All 942 of them had blood samples drawn in the 1990s, before any developed cancer. The investigators tested these samples for 25-hydroxyvitamin D — abbreviated 25(OH)D — a substance produced in the liver from vitamin D.They found that patients with high amounts of 25(OH)D indeed had a lower-than-average risk of developing colorectal tumors that were enriched with immune-system cells.“This is the first study to show evidence of the effect of vitamin D on anti-cancer immune function in actual patients, and vindicates basic laboratory discoveries that vitamin D can interact with the immune system to raise the body’s defenses against cancer,” Ogino said. “In the future, we may be able to predict how increasing an individual’s vitamin D intake and immune function can reduce his or her risk of colorectal cancer.”Funding for the study was provided by the National Institutes of Health, the Friends of Dana-Farber, the Bennett Family Foundation, the Entertainment Industry Foundation, and the Paula and Russell Agrusa Fund for Colorectal Cancer Research.last_img read more

Read More →

Let pupils skip class for family holidays, says teachers’ union (UK)

first_imgMailOnline 25 March 2015 Children should be able to skip school to go on holiday without their parents being penalised, teachers said yesterday.Union leaders said holidays are now the preserve of the rich thanks to harsher rules which punish families who go away in off-peak times.Parents have been fined up to £1,000 and even taken to court since the policy, aimed at cutting absenteeism, was introduced in 2013.But the National Union of Teachers (NUT) said yesterday that families who cannot afford hiked-up prices during school holidays should be allowed to go away in term time. http://www.dailymail.co.uk/news/article-3012042/Let-pupils-skip-class-family-holidays-says-teachers-union-Rules-mean-rich-away-peak-times.htmllast_img read more

Read More →

De Guzman re-signs for Swans

first_img De Guzman scored eight goals last season as the Swans finished ninth in the Premier League and won the Capital One Cup and he is aiming to continue that progression come August. “I had a great year at Swansea,” said the 25-year-old. “The people around the club and the fans treated me well. “It was not just the results we had; it was more about showing we can also compete with the big teams. We played better against the bigger teams. “We played well in a lot of games. We played good football and it’s refreshing playing in a team that has a good football mind. “I’m very satisfied with what happened. We did very well – we were very creative. We really put Swansea on the map.” Swansea have re-signed Jonathan de Guzman on loan for next season, the Barclays Premier League club have confirmed. The Dutch international spent last season on loan at the Liberty and Swans chairman Huw Jenkins has confirmed that the winger will be remaining in South Wales next term after agreement was reached with his parent-club Villarreal. “Everyone is happy the loan is continuing,” Jenkins told www.swanseacity.net. ”Then Jonathan will review his long-term future next summer.” center_img Press Associationlast_img read more

Read More →

Dwight Howard’s Lakers contract becomes fully guaranteed during resurgent season

first_imgLOS ANGELES — As he changed by his locker an hour before tip-off, Dwight Howard – as he often does – burst into tune.“I’m walking on sunshiiiiiine, whooooa,” he sang. “And don’t it feel good!”Howard is feeling bright after his contract became guaranteed on Tuesday afternoon. While the veteran minimum ($2.56 million) is a drop in the coffers for a player who has totaled an estimated $238 million in career earnings, it was a validation for Howard and the Lakers of a second chance that once seemed unlikely.The 34-year-old veteran was almost being ushered out of the league when the Lakers brought him in for a workout this summer, looking for a replacement for the injured DeMarcus Cousins. While the Lakers said they believed that Howard expressed a real desire to change, their non-guaranteed deal spoke of internal skepticism that he could toe the line. Trail Blazers, Grizzlies advance to NBA play-in game; Suns, Spurs see playoff dreams dashed How athletes protesting the national anthem has evolved over 17 years AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREUCLA alum Kenny Clark signs four-year contract extension with PackersBut almost midway through the season, Howard (7.1 ppg, 6.8 rpg, 1.4 bpg) has evolved into one of the team’s most important role players off the bench. And all parties are happy with how things have turned out so far.“I felt like we’ve always had a connection from conversations we’ve had where we were both opponents to each other,” Coach Frank Vogel said. “I felt like it was going to be a good fit, and when we met with him this summer that I could be an influential coach for him, and that he could bring his skill set and if he accepted the right role could really help us. All of that has played out in the way that I anticipated so far.”It’s also what Howard anticipated when he told reporters back in August after he signed, “My goal is just to win, there’s nothing else that matters.”His previous stint in Lakerland colored early expectations. Howard came to the Lakers in a 2012 trade that the franchise hoped would trumpet their arrival back onto the championship stage. The ensuing season saw the Lakers make a disappointing first-round playoff exit, and Howard left for Houston that summer in free agency.The intervening years saw him bounce to several franchises amid rumors that he was disliked in the locker room. After being cut over the summer, there was legitimate speculation that Howard – who once won three consecutive NBA Defensive Player of the Year honors – might be done in the league. Lakers practice early hoping to answer all questions Lakers, Clippers schedules set for first round of NBA playoffs center_img Howard seems all-in on that goal as well.“It’s a rare feeling, but it’s also amazing when you see, not just a team, but the city and everybody behind their team just kind of gives you an extra boost of energy,” he said. “So we can bring that feeling here to L.A. again. It’s been a while, but just something I think about, and I visualize every day. I haven’t stopped since the first day I came here, and even though we had some ups and downs, I still haven’t stopped thinking and envisioning us holding up that trophy, and parades and seeing all the people in the stands happy.”BRADLEY COMES BACKAfter a scare on Sunday night against the Pistons, Avery Bradley returned to the starting lineup on Tuesday night apparently no worse for the wear.Bradley had to be helped off the court to the locker room after rolling his right ankle, but later said he wanted to return. The Lakers held him out of the second half because he was limping.On Tuesday morning, Bradley called the incident “a freak accident,” but was glad that his season – which has already been set back once by a hairline fracture in his right leg – hadn’t hit another injury snag.“I was hoping that it wasn’t anything serious,” he said. “Once I got the X-rays back and MRI yesterday, I felt a lot more comfortable. I felt great this morning at shootaround.” Trail Blazers beat Grizzlies in play-in, earn first-round series with the Lakers Newsroom GuidelinesNews TipsContact UsReport an Error As Howard reflected on some of his challenging times on Sunday after a win over the Pistons, “Can You Stand The Rain” by New Edition was playing on a portable speaker in his locker. A reporter teasingly asked if he himself could stand the rain – and Howard got reflective.“Man, I’ve been standing in the rain for years! The sun is shining again!” Howard said. “You gotta be able to stand in the rain. That’s what makes us humans. That’s what makes us us. The ability to go through tough times and not allow it to break our character. It’s hard to do. It’s hard to go through Hell and be like, ‘OK, just smile it off.’ But you never know how close you are to your breakthrough if you just quit on yourself.”Another indication that Howard is back to his old self: The Athletic was the first to report that Howard would participate in the All-Star Weekend slam dunk contest, which he won in 2008 while famously donning a Superman-like cape.Anthony Davis said he might participate if Howard needs him as an assistant in Chicago, where he’s also expected to earn an All-Star berth. Vogel said he didn’t have strong feelings on Howard being back in the contest, but thought it reflected the care Howard has put into his training during the past year.“I do feel like part of his mission, so to speak, for this year was to repair his image,” Vogel said. “I wanted to put him in the position to do that. He’s really done it with his play, even before came here, with how he changed his body. In terms of losing the weight, and just getting him in a different kind of shape for the next phase of his career.”Vogel also used the term “great start” to describe Howard’s tenure so far, because there’s a lot more to do. The Lakers were cautious to first embrace Howard’s return, and even now that they’re closer, they expect Howard to play a supporting but important role in getting back to the Finals, where Howard last played in 2009.Related Articleslast_img read more

Read More →

Djokovic battles through to Qatar semi-finals

first_imgHowever, Djokovic’s fortunes changed in the second set when he broke the Georgian in the fifth game and slowly took control of the match.Twice a previous tournament winner in Doha, Djokovic now has a 15-1 record overall in Doha.The irrepressible Djokovic is set to play his sixth match of the week later on Thursday when he continues his doubles partnership with his brother Marko.Also through to the semi-finals is Tomas Berdych of the Czech Republic who brushed aside France’s Pierre-Hugues Herbert, one of the surprises of the tournament, 6-2, 6-4.The other semi-final also takes place on Thursday between Dusan Lajovic of Serbia and Italy’s Marco Cecchinato.Share on: WhatsApp Doha, Qatar | AFP | World number one Novak Djokovic won another gruelling battle in Doha on Thursday to continue his unbeaten start to the year and progress to the Qatar Open semi-finals.The Serb came from a set down, just like in his previous match, to beat Georgia’s Nikoloz Basilashvili 4-6, 6-3, 6-4 in a match lasting almost two hours.Djokovic will play Spain’s Roberto Bautista Agut in Friday’s semi-final, who beat three-time Grand Slam winner Stan Wawrinka in straight sets 6-4, 6-4.It is the first time Djokovic has won back-to-back matches from a set down since Cincinnati in August last year, a tournament he went on to win.As on the previous evening, where he struggled against Hungary’s Marton Fucsovics, the Serb started slowly.He lost his first service game and never recovered the break as Basilashvili, the number five seed, powered by a blistering forehand took the first set.last_img read more

Read More →

The Miami East-MVCTC FFA Chapter Seatbelt Awareness Activity Held

first_imgShare Facebook Twitter Google + LinkedIn Pinterest On Wednesday, September 18, as part of National Farm Safety and Health Awareness Week, the Miami East-MVCTC FFA Chapter held a Seatbelt Awareness Activity. As students exited the parking lot at Miami East High School, the drivers were stopped and their seatbelts were checked.All student drivers were inspected for wearing their seatbelt. They received “Smarties” for wearing their belts and “DummDumm” candies for not wearing their belts. They were reminded that, “Seatbelts are for Smarties.” Any student drivers or passengers not wearing their seatbelts were instructed to put on their seatbelt immediately.Results of the event proved that a majority of the drivers at Miami East High School do wear their seatbelt. Over 70 drivers and passengers were presented candy with 8% of drivers were not wearing their seatbelt and 92% wearing the seatbelt. Similar results as were collected last fall when 5% of drivers were not wearing their seatbelt.The first seatbelt was in a Volvo vehicle in 1849. On February 15, 1885, the seatbelt patent was given to Edward J. Claghorn. By the 1930s doctors were requesting the vehicles be equipped with the restraining device. By the 1950s they were seen regularly in automobiles. And legislation in 1966-1968 made them mandatory for all cars.The FFA’s Safety Committee would like to encourage all drivers to slowdown and wear their seatbelt. Committee members involved in this activity were Erin Baker, Anna Broerman, Carter Gilbert, Justin Hawkins, and Meadow Powers.   Junior FFA member Justin Hawkins (right) gives a “Smartie” candy to junior Rylee Puthoff and her younger brother for wearing their seatbelt.last_img read more

Read More →

Vettel is right in being cautious about his chances on Race Day

first_imgThe dust and grime have settled on the Buddh International Circuit in Greater Noida -in every sense. And after two days of hectic activity at the Indian Grand Prix in free practice and qualifying, it is clear that anyone who is going to watch Sunday’s race will get his or her money’s worth.Agreed, a lot of talk has revolved around dwindling interest this year, after the inaugural edition saw good crowds. But my point is, unlike many sports where the competitors do get a huge boost from fan support, the race drivers do not rely on the crowd to up their performances.The way this Formula One season has panned out, it has been frenetic activity for the big teams, with Red Bull again leading the charge in their inimitable style.The qualifying format is very simple and when one analyses the performance of Sebastian Vettel, again sitting on pole, he becomes the favourite to open up a huge lead in the drivers’ standings if he wins on Sunday.However, the two-time defending champion has been very defensive about his chances and even after clinching pole position says no points have been won and everything boils down to Race Day.From a fans’ point of view, the Indian GP is being held at a crucial time with the championship pretty much open. Though the battle for the drivers’ title is between Vettel and Fernando Alonso, with just six points separating them, the German will have the advantage of being right in front on the grid.For those who saw a flawless Vettel in superb form last year at the Buddh circuit, he is again on a hot streak now. The way he has won the last three races in Singapore, Japan and Korea was awesome. Yet, qualifying on Saturday was a mildly jittery one for Vettel as an error at Turn 7 on his first Q3 effort reflected vulnerability.However, the champion responded in style with a scorching lap of 1 minute 25.283s in his second attempt to beat Red Bull teammate Mark Webber. After that, Vettel stayed out, knowing that if he had to defend his position, he would return.In every sport, there are riveting rivalries which catch the eye. And in Formula One, you would imagine that the rivalry between drivers should be from different teams.Though Vettel and Webber are part of the same team, it is good to see both of them pushing each other so hard. The work the Red Bull engineers have done on the two cars in the second part of this season is awesome and the pace they produce cannot be matched.The way they started the topsyturvy season was difficult to understand, with initial races throwing up seven different winners.But now that Red Bull have found the zing again, unless something goes drastically wrong, Vettel looks unstoppable.I can understand why Vettel is trying to keep the pressure off himself by not talking too much about his chances at this point of time. Last year, he was pretty much in a comfort zone as the championship had been sealed midway through.Yet, the beauty of this sport is how the unexpected can happen.And to rule out more twists in the tale would be dicey as, despite the engineering efforts and skills of a racing driver like Vettel, it is, after all, a car. With 80,000 components bringing the beast to life, there is an element of suspense as one fault -mechanical, electrical or hydraulic -can stall the car.Sorry SchumiEven though none of these bothered Michael Schumacher’s Mercedes on Saturday, it was sad viewing to see the former champion limp along in qualifying.H aving been in the Capital for almost five days now, Schumacher has been attending media conferences and trying to remain focused on the last four races of his career. It’s clear that the seven-time F1 champion has lost the competitive edge. For those used to seeing Schumacher dominate the sport for years and his Ferrari eat up the miles on the track so fluidly, his last few days in F1 make for painful viewing.That he could not even make it to Q3 while teammate Nico Rosberg did was proof that there is no point blaming the car. And as Schumacher himself said earlier in the week, his legacy is intact, though his return to Formula One in 2010 after retiring in 2006 has been forgettable.The hardcore Schumacher fans fondly remember him for his daring and, at times, audacious driving in the Prancing Horse. And with his former teammate Felipe Massa also showing poor control of his car on the corners in Saturday’s qualifying, feeling nostalgic didn’t really help.advertisementadvertisementlast_img read more

Read More →